書名 Molecular-genetic and statistical techniques for behavioral and neural research / edited by Robert T. Gerlai
出版項 London, U.K. ; San Diego, CA : Elsevier/Academic Press, c2018
book jacket
館藏地 索書號 條碼 處理狀態
 陽明大學書庫區  WM20 M718 2018    30020101038919  在架上
稽核項 xxx, 677 p. : ill. (chiefly col.) ; 25 cm
內容 Section I. Neuroinformatics, computational models and data analysis -- Neurological biomarkers and neuroinformatics: the role of the virtual brain -- Informatics for interoperability of molecular-genetic and neurobehavioral databases -- The Allen Brain Atlas; toward understanding brain behavior and function through data acquisition, visualization, analysis and integration -- ExAtlas: online tool to integrate gene expression and gene set enrichment analyses -- Computational models: how do they help to understand neurologic diseases? -- The use of recombinant inbred strains in systems genetics and functional analyses in behavioral pharmacology -- Section II. Searching for new genes: natural genetic variation -- Spontaneous versus induced mutations: conceptual and methodological considerations for the neurobehavioral geneticist -- Reduced complexity cross design for behavioral genetics -- Collaborative cross as the next-generation mouse genetic reference population designed for dissecting complex traits -- Discovery of novel genes and other lineage-specific features through comparative genomics -- Using signatures of directional selection to guide discovery -- Section III. Discovery of new genes and new functions of genes using gene expression analyses -- Using transcriptomics to study behavior -- Genes, behavior, and next-generation sequencing: the first 10 years -- Abnormal social behaviors and dysfunction of autism-related genes associated with daily agonistic interactions in mice -- Epigenetic mechanisms of learning and memory -- Section IV. Discovery of genes and biological mechanisms: forward genetics and other screening-based methods -- Systematic screens in zebrafish shed light on cellular and molecular mechanisms of complex brain phenotypes -- The transition of zebrafish functional genetics from random mutagenesis to targeted integration -- Section V. Manipulating known genes to understand biological function: reverse genetics -- Molecular techniques used to explore glutamate receptors in synaptic plasticity and memory -- Using Herpes simplex virus type 1-based amplicon vectors for neurosceience research and gene therapy of neurologic diseases -- Cre-lox neurogenetics: history, present, and future -- Functional analysis of proteins involved in neurodegeneration using the model organism Dictyostelium: Alzheimer's, Huntington's, and Batten Disease -- The role of human endogenous retroviruses (HERVs) in the pathologies of the nervous system -- Optogenetics dissection of sleep circuits and functions -- The use of DREADDs for dissecting the contribution of cellular and neural circuit mechanisms in models of neurodegenerative disease -- Section VI. Ethical considerations -- Genes and human behavior: ethical implications -- Ethical considerations for animal use in behavioral and neural research
主題 Neurogenetics
Neuropsychology
Genetic psychology
Behavioral Research -- methods
Molecular Biology -- methods
Neurosciences -- methods
其他作者 Gerlai, R. T
國際標準書號 9780128040782 (hbk.) : US$175.00